Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yoshimi Imaeda
Terutoshi Maeda
Toshiyuki Morichika
Oliver Boris Stauch
Daisuke Kameoka
Date of Patent
September 26, 2023
Patent Application Number
18162368
Date Filed
January 31, 2023
Patent Citations
...
Patent Primary Examiner
CPC Code
Patent abstract
The problem to be solved is to provide a humanized anti-IL-6 receptor antibody AMA-containing formulation which is suitable for subcutaneous administration, wherein dimerization or deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and histidine buffer. A method of inhibiting deamidation or dimerization of such an antibody in a concentrated liquid formulation includes histidine buffer in the liquid formulation.
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