Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kayvan Niazi
Wael Tadros
Annie Shin
Date of Patent
October 3, 2023
Patent Application Number
16959424
Date Filed
January 15, 2019
Patent Citations
Patent Primary Examiner
Patent abstract
Compositions and methods are presented that allow for an enhanced immune response against a GPI-anchored tumor associated antigen by modification of the protein portion of the TAA to include a transmembrane domain and a trafficking signal that directs the modified protein to the endosomal or lysosomal compartment. Most preferably, the modified protein will no longer have a GPI anchor or GPI attachment sequence.
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