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US Patent 11780840 Tricyclic urea compounds as JAK2 V617F inhibitors

Patent 11780840 was granted and assigned to Incyte on October, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

David M. Burns

Onur Atasoylu

Song Mei

Joseph Barbosa

Haisheng Wang

Eddy W. Yue

Leah C. Konkol

Jun Pan

...

Date of Patent

October 10, 2023

Patent Application Number

17365789

Date Filed

July 1, 2021

Patent Citations

US Patent 8637235 Identification of a JAK2 mutation in polycythemia vera

US Patent 7429456 Identification of a JAK2 mutation in Polycythemia Vera

US Patent 7781199 Identification of a JAK2 mutation involved in Vaquez Polyglobulia

US Patent 7879844 Heterocyclic janus kinase 3 inhibitors

US Patent 8163767 Heterocyclic Janus Kinase 3 inhibitors

US Patent 8524867 Optimized antibodies that target CD19

US Patent 10287303 Compositions and methods for inhibiting arginase activity

US Patent 10377759 Brk inhibitory compound

...

Patent Citations Received

US Patent 12084430 Tricyclic urea compounds as JAK2 V617F inhibitors

0

US Patent 11958861 Spirocyclic lactams as JAK2 V617F inhibitors

0

Patent Primary Examiner

Charanjit Aulakh

CPC Code

Patent abstract

The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.

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