Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Daniella Ishimaru
Brandon Wustman
Mirko Hennig
David J. Lockhart
Date of Patent
October 17, 2023
Patent Application Number
18048253
Date Filed
October 20, 2022
Patent Citations
Patent Primary Examiner
Patent abstract
Polynucleotides encoding peptides, proteins, enzymes, and functional fragments thereof are disclosed. The polynucleotides of the disclosure can be effectively delivered to an organ, such as the lung, and expressed within cells of the organ. The polyribonucleotides of the disclosure can be used to treat a disease or condition associated with cilia maintenance and function, impaired function of the axoneme, such as DNAI1 or DNAH5.
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