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US Patent 11787785 Pyrazolopyridine derivatives and uses thereof

Patent 11787785 was granted and assigned to Novartis on October, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Noel Marie-France Thomsen

Artiom Cernijenko

Gary O'Brien

Rama Jain

Andrew W. Patterson

Hasnain Ahmed Malik

Simone Bonazzi

Natalie Alysia Dales

...

Date of Patent

October 17, 2023

Patent Application Number

17693759

Date Filed

March 14, 2022

Patent Citations

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US Patent 10640489 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof

US Patent 10414755 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof

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CPC Code

Patent abstract

The present disclosure relates to compounds of formula (I) and pharmaceutical compositions and their use in reducing Widely Interspaced Zinc Finger Motifs (WIZ) expression levels, or inducing fetal hemoglobin (HbF) expression, and in the treatment of inherited blood disorders (e.g., hemoglobinopathies, e.g., beta-hemoglobinopathies), such as sickle cell disease and beta-thalassemia.

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