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US Patent 11802115 Pharmaceutical formulation of odevixibat

Patent 11802115 was granted and assigned to Albireo AB on October, 2023 by the United States Patent and Trademark Office.

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 US Patent 11802115 Pharmaceutical formulation of odevixibat

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Patent abstract

The invention relates to a pharmaceutical formulation, e.g. a paediatric formulation, of odevixibat, which comprises a plurality of small particles. The formulation may be used in the treatment of liver diseases such as bile acid-dependent liver diseases, and particularly cholestatic liver diseases such as biliary atresia, progressive familial intrahepatic cholestasis (PFIC), Alagille syndrome (ALGS) and paediatric cholestatic pruritus. The invention also relates to a process for the preparation of the pharmaceutical formulation.

Infobox
Is a
Patent
Patent
Patent Applicant
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Albireo AB
Current Assignee
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Albireo AB
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11802115
Patent Inventor Names
Ann-Charlotte Dahlquist
Anna-Maria Tivert
Eva Byröd
Ingvar Ymen
Jessica Elversson
Martin Bohlin
Nils Ove Gustafsson
Per-Göran Gillberg
Rikard Bryland
Robert Lundqvist
Date of Patent
October 31, 2023
Patent Application Number
16477160
Date Filed
June 20, 2019
Patent Citations
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US Patent 11111224 Benzothia(di)azepine compounds and their use as bile acid modulators
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US Patent 7125864 Benzothiazepine derivatives for the treatment of hyperlipidemia
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US Patent 7132416 Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia
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US Patent 7132557 Amine compounds and curable compositions derived therefrom
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US Patent 7192945 Benzothiazepine derivatives
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US Patent 7192946 Benzothiazepine derivatives
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US Patent 7192947 Peptides derivatives comprising thiazepine group for the treatment of hyperlipidemic conditions
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US Patent 7226943 Benzothiepine ileal bile acid transport inhibitors
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US Patent 7238684 Benzothiadiazepine derivatives, processes for their preparation and pharmaceutical compositions containing them
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US Patent 11180465 Benzothia(di)azepine compounds and their use as bile acid modulators
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US Patent 7514421 Use of an IBAT inhibitor for the treatment of constipation
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US Patent 7615536 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic
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US Patent 7767229 Use of poly diallyamine polymers
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US Patent 7923468 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with cyclohexyl groups, method for producing the same, drugs containing said compounds and use thereof
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US Patent 7939061 Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides
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US Patent 7956085 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof
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US Patent 8048413 Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
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US Patent 8067584 Benzothiazepine derivatives
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US Patent 8101583 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof
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US Patent 8106023 1,4-benzothiepin-1, 1-dioxide derivatives with improved properties method for producing the same, drugs containing said compounds and the use thereof
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US Patent 9023368 Colonic drug delivery formulation
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US Patent 9295677 Polyhydroxylated bile acids for treatment of biliary disorders
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US Patent 9339480 Bile acid recycling inhibitors for treatment of obesity and diabetes
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US Patent 9409875 Crystal modifications of elobixibat
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US Patent 9684018 Current sense circuit that operates over a wide range of currents
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US Patent 9694018 IBAT inhibitors for the treatment of liver disease
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US Patent 9701649 Crystal modifications of elobixibat
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US Patent 9745276 Crystal modifications of elobixibat
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US Patent 9872844 Compositions and methods for the reduction or prevention of hepatic steatosis
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US Patent 11225466 Benzothiadiazepine compounds and their use as bile acid modulators
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US Patent 10183920 Crystal modifications of elobixibat
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US Patent 10428109 Process for the preparation of 1,5-benzothiazepine compounds
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US Patent 10941127 Benzothiadiazepine compounds and their use as bile acid modulators
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US Patent 10975045 Benzothiazepine compounds and their use as bile acid modulators
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US Patent 10975046 Crystal modifications of odevixibat
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US Patent 10981952 IBAT inhibitors for the treatment of liver diseases
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US Patent 10995115 Process for the preparation of 1,5-benzothiazepine compounds
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US Patent 11014898 Benzothiazepine compounds and their use as bile acid modulators
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US Patent 11267794 Benzothia(di)azepine compounds and their use as bile acid modulators
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US Patent 11306064 Benzothia(di)azepine compounds and their use as bile acid modulators
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US Patent 6906058 1,5-Benzothiazepines and their use as hypolipidaemics
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US Patent 6943189 Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG CO-A reductase inhibitors
Patent Primary Examiner
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Bethany P Barham

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