Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ralph Michael Linden
Date of Patent
October 31, 2023
Patent Application Number
17072676
Date Filed
October 16, 2020
Patent Citations
...
Patent Primary Examiner
Patent abstract
Disclosed herein is a recombinant adeno-associated virus (AAV) vector comprising (a) a variant AAV2 capsid protein, wherein the variant AAV2 capsid protein comprises at least four amino acid substitutions with respect to a wild type AAV2 capsid protein; wherein the at least four amino acid substitutions are present at the following positions in an AAV2 capsid protein sequence: 457, 492, 499 and 533; and (b) a heterologous nucleic acid comprising a nucleotide sequence encoding a gene product.
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