US Patent 11826403 Target for diabetes treatment and prevention
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US Patent 11826403 Target for diabetes treatment and prevention
Article
Patent abstract
The present invention relates to the identification of ALMS1 as the missing player involved in the regulation of the insulin-mediated glucose uptake through GLUT4 sorting vesicles, and to the down-regulation of ALMS1 by αPKC. Accordingly, the present invention relates to a molecule capable of preventing the binding of αPKC on ALMS1 for use for treating or preventing diabetes, in particular type 2 diabetes. In addition, the present invention relates to a method for identifying molecule capable of preventing the binding of αPKC on ALMS1.
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Patent Jurisdiction
Patent Number
Patent Inventor Names
Nikolai Petrovsky0
Vincent Marion0
Date of Patent
November 28, 2023
0Patent Application Number
170746580
Date Filed
October 20, 2020
0Patent Citations
Patent Primary Examiner
CPC Code
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