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US Patent 11833155 Combination therapy for treatment of myeloproliferative neoplasms

Patent 11833155 was granted and assigned to Incyte on December, 2023 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Phillip C. Liu0

Matthew Stubbs0

Date of Patent

December 5, 2023

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Patent Application Number

173370060

Date Filed

June 2, 2021

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Patent abstract

The present application relates to treatment of myeloproliferative neoplasms using the JAK1/JAK2 inhibitor, ruxolitinib, in combination with a BET protein inhibitor, 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-1,4-benzoxazin-3(4H)-one, wherein the combination is unexpectedly synergistic.

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