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US Patent 11834482 Agents modulating beta-catenin functions and methods thereof

Patent 11834482 was granted and assigned to Fog Pharmaceuticals on December, 2023 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Fog Pharmaceuticals
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Current Assignee
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Fog Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118344820
Patent Inventor Names
So Youn Shim0
Matthew Reiser Patton0
Gerard Hilinski0
Gregory L Verdine0
John Hanney McGee0
Paula Cristina Ortet0
Date of Patent
December 5, 2023
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Patent Application Number
175182470
Date Filed
November 3, 2021
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Patent Citations
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US Patent 8592377 Stitched polypeptides
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US Patent 8796418 Stabilized alpha helical peptides and uses thereof
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US Patent 8815932 Induction of alpha helix conformations in proteins and peptides
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US Patent 8889632 Stabilized p53 peptides and uses thereof
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US Patent 8895699 Stabilized compounds having secondary structure motifs
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US Patent 8921323 Methods and compositions for modulating BCL-2 family polypeptides
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US Patent 8957026 Beta-catenin targeting peptides and uses thereof
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US Patent 7192713 Stabilized compounds having secondary structure motifs
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...
Patent Primary Examiner
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Jeffrey E. Russel
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CPC Code
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C07K 2/00
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A61K 38/10
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A61K 38/08
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A61K 38/00
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C07K 7/06
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A61K 38/03
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C07K 4/00
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Patent abstract

Among other things, the present disclosure provides technologies for modulating functions of beta-catenin. In some embodiments, the present disclosure provides stapled peptides that interact with beta-catenin. In some embodiments, provided stapled peptides interact with beta-catenin at an Axin-binding site of beta-catenin. In some embodiments, the present disclosure provides compounds, compositions and methods for preventing and/or treating conditions, disorders and diseases that are associated with beta-catenin.

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