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US Patent 11839663 Radiolabelled MGL pet ligands

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Chaofeng Huang0

Jimmy T. Liang0

Gang Chen0

Date of Patent

December 12, 2023

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Patent Application Number

170369190

Date Filed

September 29, 2020

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Patent Primary Examiner

Michael G. Hartley

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CPC Code

0

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Patent abstract

The present invention relates to novel, selective, radiolabelled compound having monoacylglycerol lipase (MGL) affinity which are useful for imaging and quantifying MGL receptor expression, distribution and enzyme occupancy in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.

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