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US Patent 11840710 Methods for purification of recombinant AAV vectors

Patent 11840710 was granted and assigned to Genzyme on December, 2023 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Peter S. Gagnon0

Gina Nichols0

Paulene McLean Quigley Sheldon0

Barbara A. Thorne0

Date of Patent

December 12, 2023

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Patent Application Number

170354800

Date Filed

September 28, 2020

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Patent Citations

US Patent 6995006 Methods for generating high titer helper-free preparations of released recombinant AAV vectors

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US Patent 6989264 Methods for generating high titer helper-free preparations of released recombinant AAV vectors

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US Patent 7015026 Purification of adenovirus and AAV

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Patent Primary Examiner

Benjamin P Blumel

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Patent abstract

Provided herein are methods for the purification of recombinant adeno-associated virus (rAAV) vectors that can be used for gene transfer and specifically for gene therapy or vaccination. Recombinant AAV vectors of the invention are substantially free of in-process impurities, including production components such as cellular nucleic acids, cellular proteins, helper virus, and media components.

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