Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hang-Gyeong Chin0
Pierre O. Esteve0
Sriharsa Pradhan0
Chaithanya Ponnaluri0
Date of Patent
December 12, 2023
0Patent Application Number
174540820
Date Filed
November 9, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
Patent abstract
Provided herein, among other things, are various compositions and methods for analyzing chromatin. In some embodiments, the composition may comprise a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP and, optionally, a polymerase. In some embodiments, this method may comprise: obtaining a sample comprising chromatin, reacting the sample with the composition to selectively label the open chromatin in the sample, and analyzing the labeled sample.
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