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US Patent 11849709 Genetically modified rat models for severe combined immunodeficiency (SCID)

Patent 11849709 was granted and assigned to Hera Testing Laboratories, Inc. on December, 2023 by the United States Patent and Trademark Office.

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Patent abstract

This invention relates to the engineering of animal cells, preferably mammalian, more preferably rat, that are deficient due to the disruption of tumor suppressor gene(s) or gene product(s). In another aspect, the invention relates to genetically modified rats, as well as the descendants and ancestors of such animals, which are animal models of human cancer and methods of their use.

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