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US Patent 11850305 Method of making lipid formulations with RNA encoding immunogens

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Is a
Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118503050
Patent Inventor Names
Andrew Geall0
Date of Patent
December 26, 2023
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Patent Application Number
182316970
Date Filed
August 8, 2023
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Patent Citations
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US Patent 11596645 Delivery of RNA to trigger multiple immune pathways
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US Patent 11690863 Delivery of RNA to trigger multiple immune pathways
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US Patent 11690865 Delivery of RNA to trigger multiple immune pathways
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US Patent 11696923 Delivery of RNA to trigger multiple immune pathways
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US Patent 11707482 Delivery of RNA to trigger multiple immune pathways
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US Patent 6858225 Lipid-encapsulated polyanionic nucleic acid
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US Patent 6890554 Genetic immunization with cationic lipids
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US Patent 7250404 Lipid-mediated polynucleotide administration to deliver a biologically active peptide and to induce a cellular immune response
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...
Patent Primary Examiner
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Arthur S Leonard
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Patent abstract

RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially a neutral surface charge at physiological pH and are effective for immunisation.

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