Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Naoka Hironiwa0
Taichi Kuramochi0
Tomoyuki Igawa0
Meiri Kawazoe0
Date of Patent
December 26, 2023
0Patent Application Number
143516540
Date Filed
October 31, 2012
0Patent Citations
Patent Primary Examiner
Patent abstract
It was found that association between CH1 and CL can be suppressed by substituting amino acids that exist on the interface between CH1 and CL with electrically-charged amino acids, and that formation of heterogeneous molecules is enabled more efficiently than by introducing knobs into holes mutations into CH3 domain.
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