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US Patent 11858939 Hetero-halo inhibitors of histone deacetylase

Patent 11858939 was granted and assigned to Alkermes (company) on January, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
0

Patent attributes

Patent Applicant
Alkermes (company)
Alkermes (company)
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Current Assignee
Alkermes (company)
Alkermes (company)
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118589390
Patent Inventor Names
Andreas Bergmann0
Andreas Schoop0
Nathan Oliver Fuller0
John A. Lowe, III0
Fabian Dey0
Martin R. Jefson0
Date of Patent
January 2, 2024
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Patent Application Number
171348750
Date Filed
December 28, 2020
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Patent Citations
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US Patent 7868205 Inhibitors of histone deacetylase
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US Patent 7544695 Spirocyclic compounds
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US Patent 7834026 Spirocyclic compounds
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US Patent 7863279 Triazolopyridine carboxamide derivatives and triazolopyrimidine carboxamide derivatives, preparation thereof and therapeutic use thereof
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US Patent 7981874 Phosphorus derivatives as histone deacetylase inhibitors
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US Patent 8349825 Spirocyclic compounds
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US Patent 8461189 Pyridyl derivatives as histone deacetylase inhibitors
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US Patent 8686020 Spirocyclic compounds
0
...
Patent Primary Examiner
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Jared Barsky
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CPC Code
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A61K 31/496
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A61K 31/4965
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A61K 2300/00
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A61K 31/44
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A61K 31/444
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A61K 31/437
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A61K 31/435
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A61K 31/27
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Patent abstract

This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.

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