US Patent 11859180 Antisense oligonucleotide compositions
Patent 11859180 was granted and assigned to Ionis Pharmaceuticals on January, 2024 by the United States Patent and Trademark Office.
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US Patent 11859180 Antisense oligonucleotide compositions
The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.
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