US Patent 11865137 Sulfated oligosaccharides having anti-inflammatory activity
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US Patent 11865137 Sulfated oligosaccharides having anti-inflammatory activity
Article
Patent abstract
Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.
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Patent Inventor Names
Ding Xu0
Jian Liu0
Katelyn Arnold0
Rafal Pawlinski0
Yongmei Xu0
Date of Patent
January 9, 2024
0Patent Application Number
167611590
Date Filed
November 5, 2018
0Patent Citations
Patent Primary Examiner
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