Patent attributes
Higher quality diffusion metrics and/or diffusion-weighted images are generated from lower quality input diffusion-weighted images using a suitably trained neural network (or other machine learning algorithm). High-fidelity scalar and orientational diffusion metrics can be extracted using a theoretical minimum of a single non-diffusion-weighted image and six diffusion-weighted images, achieved with data-driven supervised deep learning. As an example, a deep convolutional neural network (“CNN”) is used to map the input non-diffusion-weighted image and diffusion-weighted images sampled along six optimized diffusion-encoding directions to the residuals between the input and output high-quality non-diffusion-weighted image and diffusion-weighted images, which enables residual learning to boost the performance of CNN and full tensor fitting to generate any scalar and orientational diffusion metrics.