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US Patent 11878027 Nicotinamide mononucleotide derivatives and their uses

Patent 11878027 was granted and assigned to Metro International Biotech, LLC on January, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Metro International Biotech, LLC

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Current Assignee

Metro International Biotech, LLC

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

David J. Livingston0

Karl D. Normington0

James M. McKearin0

Bruce Szczepankiewicz0

David A. Sinclair0

Jonathan N. Kremsky0

Date of Patent

January 23, 2024

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Patent Application Number

178735770

Date Filed

July 26, 2022

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US Patent 9975915 Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof

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Patent Primary Examiner

Patrick T. Lewis

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Patent abstract

The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

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