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US Patent 11884949 Methods of producing morphinan alkaloids and derivatives

Patent 11884949 was granted and assigned to Antheia on January, 2024 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Christina D. Smolke0

Isis Trenchard0

Kristy M. Hawkins0

Catherine Thodey0

Date of Patent

January 30, 2024

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Patent Application Number

169849000

Date Filed

August 4, 2020

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Patent Citations

US Patent 11142780 Compositions and methods for making benzylisoquinoline alkaloids, morphinan alkaloids, thebaine, and derivatives thereof

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US Patent 10544420 Engineered benzylisoquinoline alkaloid epimerases and methods of producing benzylisoquinoline alkaloids

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US Patent 11479586 Polynucleotides and polypeptides useful for making alkaloid compounds

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Patent Primary Examiner

Ganapathirama Raghu

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CPC Code

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Patent abstract

A method of producing promorphinan, morphinan, nal-opioid, and nor-opioid alkaloid products through the increased conversion of a promorphinan alkaloid to a morphinan alkaloid. The method comprises contacting the promorphinan alkaloid with at least one enzyme. Contacting the promorphinan alkaloid with the at least one enzyme converts the promorphinan alkaloid to a morphinan alkaloid.

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