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US Patent 11891388 Pyrazolopyridine compounds and uses thereof

Patent 11891388 was granted and assigned to Incyte on February, 2024 by the United States Patent and Trademark Office.

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 US Patent 11891388 Pyrazolopyridine compounds and uses thereof

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Patent abstract

Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Incyte
Incyte
0
Current Assignee
Incyte
Incyte
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
118913880
Patent Inventor Names
Alexander Sokolsky0
Hai Fen Ye0
Jun Pan0
Kai Liu0
Oleg Vechorkin0
Qinda Ye0
Wenqing Yao0
Date of Patent
February 6, 2024
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Patent Application Number
175588240
Date Filed
December 22, 2021
0
Patent Citations
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US Patent 7105532 Pyrazolo[3,4-c]pyridines as gsk-3 inhibitors
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US Patent 7166293 Angiogenesis inhibitors
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US Patent 7259165 Heterocyclyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
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US Patent 7345178 Sirtuin modulating compounds
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US Patent 7429609 Pyrazole compound and medicinal composition containing the same
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US Patent 7576087 Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands
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US Patent 7919487 Heteroaryl compounds
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US Patent 7968719 Indazole derivatives as inhibitors of hormone sensitive lipase
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US Patent 8106190 2-aminobenzamide derivatives
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US Patent 8450335 2,4-disubstituted pyrimidines useful as kinase inhibitors
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US Patent 8546403 Compounds that modulate intracellular calcium
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US Patent 8637507 Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
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US Patent 8722691 Azolopyrimidines as inhibitors of cannabinoid 1 activity
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US Patent 8987273 Substituted imidazo[1,2-B]pyridazines
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US Patent 9090593 Bicyclic compounds as Pim inhibitors
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US Patent 9260425 Pyrazolo[3,4-c]pyridine compounds and methods of use
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US Patent 9284319 Heterocyclyl aminoimidazopyridazines
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US Patent 9320737 Substituted imidazopyridazines
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US Patent 9718818 Compounds inhibiting leucine-rich repeat kinase enzyme activity
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US Patent 9730929 Substituted aminoimidazopyridazines
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US Patent 10266530 Pyrazolopyridine compounds and uses thereof
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US Patent 10280164 Pyrazolopyridone compounds and uses thereof
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US Patent 10435405 Pyrazolopyridine compounds and uses thereof
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US Patent 10722495 Cyanoindazole compounds and uses thereof
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US Patent 10745388 Indazole compounds and uses thereof
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US Patent 10752635 Indazole compounds and uses thereof
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US Patent 10800761 Carboxamide compounds and uses thereof
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US Patent 10899755 Benzothiazole compounds and uses thereof
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US Patent 11242343 Pyrazolopyridine compounds and uses thereof
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US Patent 10934288 Pyrazolopyridine compounds and uses thereof
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US Patent 11014929 Pyrazolopyrimidine compounds and uses thereof
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US Patent 11066394 Solid forms of an HPK1 inhibitor
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US Patent 11299473 Benzimidazole and indole compounds and uses thereof
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US Patent 11406624 Pyrazolopyridine compounds and uses thereof
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US Patent 11492354 Indazole compounds and uses thereof
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US Patent 11542265 Pyrazolopyrimidine compounds and uses thereof
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US Patent 6916927 Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3′,5′-monophosphate phosphodiesterase (cGMP-PDE5) for the treatment of sexual dysfunction
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Patent Primary Examiner
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Niloofar Rahmani
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CPC Code
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C07D 471/04
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