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US Patent 11891448 Glycated CD59 peptides, their preparation, and uses thereof

Patent 11891448 was granted and assigned to President and Fellows of Harvard College on February, 2024 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides glycated Amadori products of the CD59 peptide and fragments thereof to be used as tools and among methods for the diagnosis and prognosis of pre-diabetes and diabetes. Certain aspects of the invention include glycated Amadori products of CD59 and fragments thereof to be used for the generation of antibodies and antibody fragments. Still other aspects of the invention include methodologies for the preparation of glycated Amadori products of CD59, fragments thereof, the inventive antibodies, and antibody fragments.

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