US Patent 11891635 Nucleic acid sequence replacement by NHEJ
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US Patent 11891635 Nucleic acid sequence replacement by NHEJ
Article
Patent abstract
A method for modifying double stranded DNA (dsDNA) employing an RNA guided DNA endonuclease to generate two double strand breaks in the dsDNA molecule to be modified, and replacement of the sequence positioned between the double strand breaks with a substitute DNA sequence using the non-homologous end joining (NHEJ) pathway, and corresponding kits and compositions for modifying double stranded DNA molecules.
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Patent Number
Patent Inventor Names
Eric Danner0
Ralf Kühn0
Date of Patent
February 6, 2024
0Patent Application Number
169563650
Date Filed
December 21, 2018
0Patent Citations
Patent Primary Examiner
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