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US Patent 11903963 Short-acting heparin-based anticoagulant compounds and methods

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Zhangjie Wang0

Po-Hung Hsieh0

Jian Liu0

Yongmei Xu0

Date of Patent

February 20, 2024

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Patent Application Number

164928580

Date Filed

March 12, 2018

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Patent Citations

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US Patent 10286047 Treatment and prevention of remote ischemia-reperfusion injury

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US Patent 11633424 Cell protective methods and compositions

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US Patent 6861254 Heparan sulfate D-glucosaminyl 3-O-sulfotransferases, and uses therefor

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US Patent 7101859 Use of lipid conjugates in the treatment of diseases

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Patent Primary Examiner

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CPC Code

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Patent abstract

Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided.

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