Systems and methods for deploying software updates in hybrid workspace environments are described. In some embodiments, an Information Handling System (IHS) may include a processor and a memory coupled to the processor, the memory having program instructions stored thereon that, upon execution, cause the IHS to: consolidate an Operating System (OS) and Basic Input/Output System (BIOS) inventory with a plurality of workspace inventories; resolve dependencies among a plurality of updates based upon the consolidated inventories to identify an order of deployment; and deploy the plurality of updates in the order of deployment.