Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Matthew Randolph Lee0
Anthony Joseph Varano, Jr.0
Thomas P. Bobinski0
Date of Patent
February 27, 2024
0Patent Application Number
175652310
Date Filed
December 29, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
Patent abstract
The present invention relates to indoline-based compounds that inhibit Rho-associated protein kinase (ROCK) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of inhibiting ROCK activity and methods for treating, for example cerebral cavernous malformation syndrome (CCM) and cardiovascular diseases using the compounds and pharmaceutical compositions of the present invention.
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