A process for RFID certification of carton content. Cartons may be packed with a number of RFID-tagged items and sealed. A carton may then be placed in the proximity of a scanner, which may verify the number and type of items present in the container. The carton ID information and measured RFID data of the carton contents may then be compared to a database, and an RFID pack certification label prepared for the carton if there is no mismatch. Cartons may then be scanned after unloading at a distribution center and again after they are reloaded, for example by passing them through a door portal. Such a method may substantially reduce the costs of scanning and tracking items in a supply chain.