An orthodontic wire bending device includes a providing part, a bending unit and a cutting part. The providing part is configured to provide a wire. The bending unit is disposed at a front side of the providing part, and includes a fixing part and a bending part. The fixing part is configured to fix the wire. The bending part is configured to bend the wire fixed by the fixing part. The cutting part is configured to cut the wire bent by the bending part. The bending part includes a bending module, and the bending module is rotated along a circumferential direction or moves along a direction to make contact with at least one side of the wire for bending the wire.