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US Patent 11926867 Generating capture probes for spatial analysis

Patent 11926867 was granted and assigned to 10X Genomics on March, 2024 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Yifeng Yin0

Michael Schnall-Levin0

Eswar Prasad Ramachandran Iyer0

Date of Patent

March 12, 2024

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Patent Application Number

181851180

Date Filed

March 16, 2023

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Patent Citations

US Patent 6875572 Nucleic acid detection assays

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US Patent 6890741 Multiplexed detection of analytes

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US Patent 6897023 Method for determining relative abundance of nucleic acid sequences

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US Patent 6913881 Methods and compositions for detecting target sequences

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US Patent 6942968 Array compositions for improved signal detection

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US Patent 6969488 System and apparatus for sequential processing of analytes

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US Patent 7001792 Ultra-fast nucleic acid sequencing device and a method for making and using the same

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US Patent 7011944 Invasive cleavage of nucleic acids

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Patent Citations Received

US Patent 12129516 Quantitative and automated permeabilization performance evaluation for spatial transcriptomics

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US Patent 12071655 Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis

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US Patent 12110541 Methods for preparing high-resolution spatial arrays

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Patent abstract

The present disclosure relates to compositions and methods for generating capture probes on a substrate for identifying the location of analytes in a biological sample.

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