Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yuka Yamaguchi0
Hidehito Yasukawa0
Shinji Okabe0
Date of Patent
March 19, 2024
0Patent Application Number
166443550
Date Filed
September 7, 2018
0Patent Citations
Patent Primary Examiner
Patent abstract
Aqueous pharmaceutical compositions containing a fusion protein of an antibody and a lysosomal enzyme as an active ingredient, which are stable enough to be marketed, are disclosed. The aqueous pharmaceutical composition, for example, comprises the fusion protein of the antibody and the lysosomal enzyme at a concentration of 0.5 to 20 mg/mL, sodium chloride at a concentration of 0.3 to 1.2 mg/mL, sucrose at a concentration of 50 to 100 mg/mL, a nonionic surfactant at a concentration of 0.15 to 3 mg/mL, a buffer at a concentration of 3 to 30 mM, and is adjusted to pH 5.0 to 7.5.
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