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US Patent 11938475 Flow cells with hydrogel coating

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Kenny Chen0

Gary Mark Skinner0

John A. Moon0

M. Shane Bowen0

Jonathan Mark Boutell0

Hongji Ren0

Alex Nemiroski0

Date of Patent

March 26, 2024

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Patent Application Number

171141340

Date Filed

December 7, 2020

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Patent Citations

US Patent 8778848 Patterned flow-cells useful for nucleic acid analysis

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US Patent 10619204 Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid

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US Patent 8603791 Nucleic acid sample preparation

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US Patent 8822346 Method and apparatus for self-aligned layer removal

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Patent Primary Examiner

0

Patent abstract

In an example of the method, a functionalized coating layer is applied in depressions of a patterned flow cell substrate. The depressions are separated by interstitial regions. A primer is grafted to the functionalized coating layer to form a grafted functionalized coating layer in the depressions. A hydrogel is applied on at least the grafted functionalized coating layer.

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