A vehicle control system receives signals from sensors on board a first vehicle and plural other, second vehicles. Based on the signals received from the sensors, the system determines a brake assessment of a brake system, where the brake assessment includes a state of health of the brake system and/or a location of interest of a leak in the brake system. The system controls movement of the first vehicle and the second vehicles relative to at least one remote vehicle system based at least in part on the brake assessment that is determined.