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US Patent 11939384 Antibody variable domains targeting the NKG2D receptor

Patent 11939384 was granted and assigned to Dragonfly Therapeutics, Inc. on March, 2024 by the United States Patent and Trademark Office.

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 US Patent 11939384 Antibody variable domains targeting the NKG2D receptor

Article

Patent abstract

Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Dragonfly Therapeutics, Inc.
Dragonfly Therapeutics, Inc.
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Current Assignee
Dragonfly Therapeutics, Inc.
Dragonfly Therapeutics, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119393840
Patent Inventor Names
Ann F. Cheung0
Asya Grinberg0
Bianka Prinz0
Bradley M. Lunde0
Gregory P. Chang0
William Haney0
Date of Patent
March 26, 2024
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Patent Application Number
185014130
Date Filed
November 3, 2023
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Patent Citations
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US Patent 11124582 FLT3L-FC fusion proteins
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US Patent 7112324 CD 19×CD3 specific polypeptides and uses thereof
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US Patent 7820166 Potent T cell modulating molecules
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US Patent 9102736 Multispecific deimmunized CD3-binders
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US Patent 9273136 Fully human anti-human NKG2D monoclonal antibodies
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US Patent 9493578 Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
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US Patent 9562109 Stable heterodimeric antibody design with mutations in the Fc domain
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US Patent 9587036 Cross-species-specific PSMAxCD3 bispecific single chain antibody
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US Patent 9637557 Production of heteromultimeric proteins
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US Patent 9683053 Hetero-dimeric immunoglobulins
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US Patent 9690969 Information processing apparatus, non-transitory computer readable medium, and information processing method
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US Patent 9718893 Bispecific antibody molecule
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US Patent 9951145 CH3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
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US Patent 9963513 Method for the selection of antibodies against BCMA
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US Patent 10040853 Methods and compositions involving NKG2D inhibitors and cancer
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US Patent 10047167 Methods for producing fabs and bi-specific antibodies
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US Patent 10059765 Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
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US Patent 10377827 Antigen binding proteins that bind c-met
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US Patent 10421807 Interleukin-31 monoclonal antibody
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US Patent 10526409 Antibodies against human NKG2D and uses thereof
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Patent Primary Examiner
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Chun W Dahle
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