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US Patent 11944972 Concentrating particles in a microfluidic device

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119449720
Patent Inventor Names
Kyle C. Smith0
Mehmet Toner0
Ravi Kapur0
Date of Patent
April 2, 2024
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Patent Application Number
173355100
Date Filed
June 1, 2021
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Patent Citations
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US Patent 7837040 Acoustic concentration of particles in fluid flow
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US Patent 8021614 Devices and methods for enrichment and alteration of cells and other particles
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US Patent 8186913 Systems and methods for particle focusing in microchannels
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US Patent 10150116 Concentrating particles in a microfluidic device
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US Patent 8906322 Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields
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US Patent 11052393 Concentrating particles in a microfluidic device
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US Patent 7560267 Apparatus and methods for on-chip monitoring of cellular reactions
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US Patent 7641865 Flow control through plural, parallel connecting channels to/from a manifold
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Patent Primary Examiner
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Brian J. Sines
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CPC Code
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B01L 2200/0652
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B01L 2200/0647
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A61K 35/28
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G01N 1/4077
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G01N 15/0255
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G01N 15/0618
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G01N 15/1484
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B01L 3/502753
0
...
Patent abstract

A microfluidic device includes: a first microfluidic channel; a second microfluidic channel extending along the first microfluidic channel; and a first array of islands separating the first microfluidic channel from the second microfluidic channel, in which each island is separated from an adjacent island in the array by an opening that fluidly couples the first microfluidic channel to the second microfluidic channel, in which the first microfluidic channel, the second microfluidic channel, and the islands are arranged so that a fluidic resistance of the first microfluidic channel increases relative to a fluidic resistance of the second microfluidic channel along a longitudinal direction of the first microfluidic channel such that, during use of the microfluidic device, a portion of a fluid sample flowing through the first microfluidic channel passes through one or more of the openings between adjacent islands into the second microfluidic channel.

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