Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hannah E. Petrek0
Aiming Yu0
Meijuan Tu0
Pui Yan Ho0
Qianyu Zhang0
Joseph L. Jilek0
Date of Patent
April 2, 2024
0Patent Application Number
170562030
Date Filed
May 21, 2019
0Patent Citations
Patent Primary Examiner
CPC Code
Patent abstract
Provided are hybrid tRNA/pre-miRNA molecules, e.g., comprising a single tRNA and one, two or more pre-miRNA molecules, useful for the production and therapeutic delivery of an inserted RNA sequence, e.g., one or more miRNAs. Also provided are liposomes and nanoparticles that include the hybrid tRNA/pre-miRNA molecules. Methods of treating cancer by administration of the hybrid tRNA/pre-miRNA molecules are also provided.
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