Patent 11952349 was granted and assigned to Nuvation Bio on April, 2024 by the United States Patent and Trademark Office.
The disclosure relates to anti-cancer compounds derived from a payload which binds to poly(ADP-ribose) polymerase (PARP) and a nuclear steroid-targeting epitope (B of Formula I), which components are covalently linked via a linker, to products containing the same, as well as to methods of their use and preparation.