US Patent 11952586 B-cell cultivation method
Patent 11952586 was granted and assigned to Hoffmann-La Roche Limited on April, 2024 by the United States Patent and Trademark Office.
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US Patent 11952586 B-cell cultivation method
Article
Patent abstract
Herein is reported a method for the co-cultivation of single deposited B-cells, which can be of any source, with EL-4 B5 feeder cells in a suitable co-cultivation medium. In the herein reported methods the EL-4 B5 cells have been irradiated with a dose of less than 40 Gy, preferably 9.5 Gy or less. Thereby the EL-4 B5 cells have a higher viability and maintain the ability to divide in cultivation at doses less than 6 Gy.
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Patent Applicant
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Patent Number
Patent Inventor Names
Friederike Jung0
Sonja Offner0
Date of Patent
April 9, 2024
0Patent Application Number
168882130
Date Filed
May 29, 2020
0Patent Citations
Patent Primary Examiner
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