Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yi-Zhou Quan0
Wenyan Li0
Zheng-Yi Chen0
Date of Patent
April 23, 2024
0Patent Application Number
181544740
Date Filed
January 13, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
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