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US Patent 11963981 Chimeric antigen receptor

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Shaun Cordoba0

Biao Ma0

Simon Thomas0

Mathieu Ferrari0

Shimobi Onuoha0

Martin Pulé0

Evangelia Kokalaki0

Date of Patent

April 23, 2024

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Patent Application Number

170546700

Date Filed

May 15, 2019

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Patent Citations

US Patent 11091532 T cell which co-expresses a CD19 chimeric antigen receptor and a CD22 chimeric antigen receptor

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US Patent 11590170 Chimeric antigen receptor

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US Patent 10457730 Chimeric antigen receptor (CAR) comprising a CD19-binding domain

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US Patent 11180553 Chimeric antigen receptor

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Patent Primary Examiner

Jessica H Roark

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Patent abstract

The present invention provides a chimeric antigen receptor (CAR) which binds a target antigen having a bulky extracellular domain, wherein the CAR comprises a Fab antigen binding domain. The present invention also provides nucleic acid sequences and constructs encoding such a CAR, cells expressing such a CAR and their therapeutic uses.

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