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US Patent 11965164 Amphiphilic polynucleotides

Patent 11965164 was granted and assigned to Duke University on April, 2024 by the United States Patent and Trademark Office.

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Patent abstract

Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.

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