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US Patent 11965186 Nucleic acid-guided nickases

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 US Patent 11965186 Nucleic acid-guided nickases

Article

Patent abstract

The present disclosure provides engineered nucleic acid-guided nickases and optimized scaffolds for making rational, direct edits to nucleic acids in live cells.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
119651860
Patent Inventor Names
Benjamin Mijts0
Juhan Kim0
Date of Patent
April 23, 2024
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Patent Application Number
176762180
Date Filed
February 20, 2022
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Patent Citations
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US Patent 7166443 Methods, compositions, and automated systems for separating rare cells from fluid samples
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US Patent 8332160 Systems and methods for engineering nucleic acid constructs using scoring techniques
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US Patent 9361427 Scar-less multi-part DNA assembly design automation
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US Patent 9499855 Compositions, methods, and computer systems related to making and administering modified T cells
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US Patent 9776138 Membrane filtration device having a hygienic suspension arrangement
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US Patent 9790490 CRISPR enzymes and systems
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US Patent 9896696 Compositions and methods for modifying genomes
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US Patent 9982278 CRISPR enabled multiplexed genome engineering
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US Patent 9982279 Nucleic acid-guided nucleases
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US Patent 9988624 Microbial strain improvement by a HTP genomic engineering platform
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US Patent 10017760 Methods for generating barcoded combinatorial libraries
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US Patent 10711284 CRISPR enabled multiplexed genome engineering
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US Patent 10724021 Nucleic acid-guided nucleases
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US Patent 10731180 CRISPR enabled multiplexed genome engineering
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US Patent 10745678 Nucleic acid-guided nucleases
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US Patent 10767169 Nucleic acid-guided nucleases
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US Patent 10837021 Curing for recursive nucleic acid-guided cell editing
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US Patent 10870761 High-conductive carbon black with low viscosity
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US Patent 10876102 Engineered enzymes
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US Patent 10883077 Methods for controlling the growth of prokaryotic and eukaryotic cells
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US Patent 10927385 Increased nucleic-acid guided cell editing in yeast
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US Patent 6837995 Device for concentrating and purifying macromolecules
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Patent Primary Examiner
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Suzanne M Noakes
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