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US Patent 11965215 Methods and systems for analyzing nucleic acid molecules

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 US Patent 11965215 Methods and systems for analyzing nucleic acid molecules

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Patent abstract

Processes and materials to detect cancer from a biopsy are described. In some cases, cell-free nucleic acids can be sequenced, and the sequencing result can be utilized to detect sequences derived from a neoplasm. Detection of somatic variants occurring in phase can indicate the presence of cancer in a diagnostic scan and a clinical intervention can be performed.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119652150
Patent Inventor Names
Arash Ash Alizadeh0
David M. Kurtz0
Maximilian Diehn0
Date of Patent
April 23, 2024
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Patent Application Number
181678040
Date Filed
February 10, 2023
0
Patent Citations
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US Patent 8105769 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
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US Patent 8318433 Methods and compositions for tagging and identifying polynucleotides
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US Patent 8580497 Methods for detection of the oncogenic T1796A B-Raf mutation
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US Patent 8722368 Method for preparing a counter-tagged population of nucleic acid molecules
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US Patent 8741606 Method of tagging using a split DBR
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US Patent 8835358 Digital counting of individual molecules by stochastic attachment of diverse labels
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US Patent 9035036 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
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US Patent 9340830 Optimization of multigene analysis of tumor samples
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US Patent 9598731 Systems and methods to detect rare mutations and copy number variation
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US Patent 9752188 Methods of lowering the error rate of massively parallel DNA sequencing using duplex consensus sequencing
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US Patent 9834822 Systems and methods to detect rare mutations and copy number variation
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US Patent 9840743 Systems and methods to detect rare mutations and copy number variation
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US Patent 9850523 Methods for multi-resolution analysis of cell-free nucleic acids
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US Patent 9902992 Systems and methods to detect rare mutations and copy number variation
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US Patent 9920366 Methods and systems for detecting genetic variants
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US Patent 10501810 Systems and methods to detect rare mutations and copy number variation
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US Patent 10704085 Systems and methods to detect rare mutations and copy number variation
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US Patent 10704086 Systems and methods to detect rare mutations and copy number variation
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US Patent 11384394 Methods and systems for genetic analysis
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US Patent 11447833 Methods for preparing nucleic acid libraries for sequencing
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US Patent 11634779 Methods and systems for analyzing nucleic acid molecules
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US Patent 11783912 Methods and systems for analyzing nucleic acid molecules
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Patent Primary Examiner
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Joseph Woitach
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