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US Patent 11969517 Compositions and methods for macrophage conversion

Patent 11969517 was granted and assigned to Drexel University on April, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Drexel University
Drexel University
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Current Assignee
Drexel University
Drexel University
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119695170
Patent Inventor Names
Sina Nassiri0
Kara L. Spiller0
Date of Patent
April 30, 2024
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Patent Application Number
174445980
Date Filed
August 6, 2021
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Patent Citations
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US Patent 8430831 Device, system, and method for controllably reducing inflammatory mediators in a subject
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US Patent 8440185 Compositions and methods for the treatment of immunologic disorders
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US Patent 8518879 Skin cream
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Patent Primary Examiner
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Prema M Mertz
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CPC Code
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A61K 38/2026
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Patent abstract

One aspect of the invention provides a method of treating a chronic wound including administering to the wound at least one agent from a delivery system wherein the agent induces sequential conversion of a first population of wound macrophages in the wound to M2A macrophages and a second population of wound macrophages to M2C macrophages. The sequential conversion of the wound macrophages promotes tissue remodeling.

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