Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Samantha Vellucci0
Drew Goodman0
Mark Stamatios Kokoris0
Jagadeeswaran Chandrasekar0
Kendall Berg0
Lacey Merrill0
Aaron Jacobs0
Dylan O'Connell0
...
Date of Patent
April 30, 2024
0Patent Application Number
169599850
Date Filed
December 27, 2018
0Patent Primary Examiner
Patent abstract
The invention relates to compounds, methods and compositions for improving on nucleic acid polymerization, including DNA replication by in vitro primer extension to generate, for example, polymers for nanopore-based single molecule sequencing of a DNA template. A nucleic acid polymerase reaction composition is provided with polymerization enhancement moieties, which allows enhanced DNA polymerase activity with nucleotide analogs, resulting in improved length of primer extension products for sequencing applications.
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