Systems and methods for encryption/decryption based on liveness-verified biometric data that cannot be stolen/spoofed. In various embodiments, the disclosed systems and methods facilitate encryption/decryption of data through controlling access to keys via liveness-verified biometric data. Liveness-verified biometric data may, in various embodiments, be derived from facial features, fingerprints, voice recognition, DNA, etc. Generally, if the liveness and identity of the requesting individual cannot be verified, then the individual will not be permitted to encrypt/decrypt data using the disclosed systems and methods.