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US Patent 11975059 IL-15-based fusions to IL-12 and IL-18

Patent 11975059 was granted and assigned to Altor BioScience on May, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Altor BioScience

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Current Assignee

Altor BioScience

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Bai Liu0

Hing C. Wong0

Lijing You0

Robert Newman0

Peter Rhode0

Lin Kong0

Warren D. Marcus0

Date of Patent

May 7, 2024

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Patent Application Number

185265980

Date Filed

December 1, 2023

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Patent Citations

US Patent 9328159 Multimeric IL-15 soluble fusion molecules and methods of using same

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US Patent 9428573 Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US Patent 9464127 Fusion molecules and IL-15 variants

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US Patent 9925247 IL-15-based molecules and methods of use thereof

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US Patent 10150805 Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US Patent 10450359 IL-15 variants and uses thereof

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US Patent 11129883 IL-15-based fusions to IL-12 and IL-18

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US Patent 11571470 IL-15-based fusions to IL-12 and IL-18

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Patent Primary Examiner

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CPC Code

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Patent abstract

The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

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