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US Patent 11976130 Antibodies against claudin 18.2 useful in cancer diagnosis

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Stefan Woll0

Rita Mitnacht-Kraus0

Ugur Sahin0

Ozlem Tureci0

Date of Patent

May 7, 2024

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Patent Application Number

160377590

Date Filed

July 17, 2018

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Patent Citations

US Patent 7193074 Secreted and transmembrane polypeptides and nucleic acids encoding the same

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US Patent 7893211 Mammalian genes; related reagents and methods

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US Patent 8088588 Genetic products differentially expressed in tumors and the use of thereof

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US Patent 8148507 Nucleic acid encoding TNFx protein

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US Patent 8168427 Monoclonal antibodies against claudin-18 for treatment of cancer

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US Patent 8425902 Monoclonal antibodies against claudin-18 for treatment of cancer

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US Patent 8426573 Nucleic acids encoding TNFγ

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US Patent 8586047 Genetic products differentially expressed in tumors and the use thereof

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Patent Primary Examiner

Meera Natarajan

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CPC Code

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Patent abstract

The invention relates to antibodies directed against an epitope located within the C-terminal portion of CLDN18.2 which are useful, for example, in diagnosing cancer and/or in determining whether cancer cells express CLDN18.2.

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