US Patent 11976133 Bispecific T cell engagers
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US Patent 11976133 Bispecific T cell engagers
Article
Patent abstract
Provided are bispecific T Cell Engagers. More specifically, the invention is directed to bispecific molecules that bind to DLL3, MUC17 or CLD18 and activate CD (cluster of differentiation) molecules (e.g. CD3, CD28 and CD137). Also provided are methods of treating an ailment such as cancer using an antibody (or fragment) against DLL3, MUC17 or CLD18 paired with an antibody (or fragment) of an agonist antibody that activates CD3, CD28 and/or CD137.
Infobox
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Patent Jurisdiction
Patent Number
Patent Inventor Names
Jackie Sheng0
Margaret Karow0
Richard Yau0
Date of Patent
May 7, 2024
0Patent Application Number
171646990
Date Filed
February 1, 2021
0Patent Citations
Patent Primary Examiner
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